Epidermolysis bullosa (EB) is often referred to as the 'The Worst Disease You've Never Heard Of™' due to the constant pain these children must suffer with. There is now hope for a treatment in the form of SD-101, an ointment being developed by Scioderm Inc.
In this exclusive interview with Dr Robert Ryan, CEO of Scioderm discusses the clinical trials underway with SD-101.
At present there is no product approved for the treatment of EB and care is often focused on replacement of bandages to protect the skin from tearing and prevent infection.
EB is a group of rare genetic rare disorders that manifest as blistering or erosion of the skin. In some cases, the epithelial lining of other organs can be affected. There are 4 types of genetically inherited EB and in order of prevalence, they are Simplex (EBS), Dystrophic (DEB), Junctional (JEB) and Kindler. In the more severe forms of the disease, blistering can lead to deformities including fusion of the fingers and toes, secondary skin infections, sepsis and even death.